Research Article

Effect of the Entorhinal Cortex on Ictal Discharges in Low-Mg2+-Induced Epileptic Hippocampal Slice Models

Table 3

Statistical analysis results of VPA effects on the duration of interictal discharges in the two slice models (mean ± SEM, ).

Duration (ms)
CA3aCA3bCA3cCA1DG

HP Control184.9 ± 51.2 191.0 ± 41.2 176.7 ± 32.3 175.0 ± 37.7 151.3 ± 29.1
VPA197.4 ± 28.1186.9 ± 36.8173.1 ± 41.2210.9 ± 40.5155.4 ± 23.4
Wash194.1 ± 62.9186.7 ± 42.3162.5 ± 38.7200.6 ± 22.9145.3 ± 20.7

EC-HP Control218.1 ± 20.6 222.4 ± 16.6 222.6 ± 11.3 211.4 ± 63.5 184.4 ± 18.8
VPA215.6 ± 50.4241.7 ± 32.0210.5 ± 22.7221.5 ± 67.6185.2 ± 17.1
Wash222.8 ± 38.6240.2 ± 14.8200.7 ± 17.6229.5 ± 57.3168.5 ± 14.9

HP: hippocampal slice; EC-HP: combined EC-hippocampal slice.