Research Article
Effect of the Entorhinal Cortex on Ictal Discharges in Low-Mg2+-Induced Epileptic Hippocampal Slice Models
Table 3
Statistical analysis results of VPA effects on the duration of interictal discharges in the two slice models (mean ± SEM,
).
| | | Duration (ms) | | | CA3a | CA3b | CA3c | CA1 | DG |
| HP | Control | 184.9 ± 51.2 | 191.0 ± 41.2 | 176.7 ± 32.3 | 175.0 ± 37.7 | 151.3 ± 29.1 | VPA | 197.4 ± 28.1 | 186.9 ± 36.8 | 173.1 ± 41.2 | 210.9 ± 40.5 | 155.4 ± 23.4 | Wash | 194.1 ± 62.9 | 186.7 ± 42.3 | 162.5 ± 38.7 | 200.6 ± 22.9 | 145.3 ± 20.7 |
| EC-HP | Control | 218.1 ± 20.6 | 222.4 ± 16.6 | 222.6 ± 11.3 | 211.4 ± 63.5 | 184.4 ± 18.8 | VPA | 215.6 ± 50.4 | 241.7 ± 32.0 | 210.5 ± 22.7 | 221.5 ± 67.6 | 185.2 ± 17.1 | Wash | 222.8 ± 38.6 | 240.2 ± 14.8 | 200.7 ± 17.6 | 229.5 ± 57.3 | 168.5 ± 14.9 |
|
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HP: hippocampal slice; EC-HP: combined EC-hippocampal slice.
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