Review Article

Astrocyte-Synapse Structural Plasticity

Figure 2

Perisynaptic astrocytic processes (PAPs) are motile. Z-stack projection of confocal images showing hippocampal CA1 dendritic spines (mcherryf, red) and PAPs (eGFPf, green) recorded in the stratum radiatum of organotypic hippocampal slice cultures. Neurons and astrocytes were virally infected with membrane targeted fluorescent proteins by injection. The labeled structures were monitored every 2 min to reveal PAP movements around spines. Square size: 3 × 3 μm (original data).
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