G-Protein Coupled Receptor-Evoked Glutamate Exocytosis from Astrocytes: Role of Prostaglandins
Figure 4
COX blockers strongly inhibit the exocytosis of glutamate evoked by activation of group I mGluR and of purinergic P2Y1 receptor. (a), (b) Quantitative histograms represent the total number of fusion events evoked by either DHPG (100 μM, ) or 2MeSADP (20 μM, ) in the presence of COX blockers, INDO (1 μM; , , resp.) or ASA (10 μM, , , resp.). Data are ± SEM of 4 cells. Statistical significance of inhibition with receptor antagonists was calculated using t-test (**).
