Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model
Figure 1
Recurrent seizure behavior occurrence in the chronic phase after CTZ induced seizure rats. (a) Bar chart showing the seizure behavior occurrence within 6-month period after CTZ induced acute seizure in individual rats studied. DMSO control rats () were represented with white bar and CTZ rats () were represented with either black strip bars () or color bars () for rats without or with recurrent seizure observed, respectively. (b) Bar chart showing the group maximal seizure scores obtained from the DMSO control rats () and CTZ rats () recorded for 6 months after CTZ induction of the seizure (*, ***, in comparison with the DMSO control).
