Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model

Table 1

Recurrent seizure behavior (Racine score IV-V behavior) occurrence in the chronic phase in CTZ induced seizure rats.

Group	𝑛	Mortality rate	Racine III recurrent seizure rate	Racine IV-V recurrent seizure rate	Seizure IV-V latency (days)	Acute seizure score	Recurrent seizure score
CTZ	13	30.8%; (𝑛=4/13)	46.2%; (𝑛=6/13)	46.2%; (𝑛=6/13)	76.3±24.8; (𝑛=6)	4.75±0.16^∗∗∗; (𝑛=10)	2.60±0.72^∗; (𝑛=10)
DMSO	8	0%; (𝑛=0/8)	12.5%; (𝑛=1/8)	0%; (𝑛=0/8)	—	0; (𝑛=8)	0.38±0.38; (𝑛=8)

^∗𝑃<0.05, ^∗∗∗𝑃<0.001, in comparison with the DMSO control.