Protective Effects of Ginkgo biloba Extract EGb 761 against Noise Trauma-Induced Hearing Loss and Tinnitus Development

Figure 2

Validation of the hearing threshold ASR paradigm. Given are the mean response amplitudes in mN (±95% confidence interval) for all vehicle treated animals (upper panels) and all EGb 761 treated animals (lower panels) over all prestimulus intensities in dB SPL for the different stimulation frequencies of pre- and startle stimuli. The “pretrauma” (blue) and “posttrauma” (red) data are presented with the corresponding 𝐹 statistics of the 1-factorial ANOVAs. Note that all statistics were significant, demonstrating that the animals were always (pre- and posttrauma = trauma status) responding to the 90 dB SPL startle stimulus and the different prestimuli.