Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors

<div>Neither Abeta(1-42) nor ifenprodil affects fEPSPs. Representative fEPSPs are shown before (grey) and after treatment in the upper panel. Neither Abeta(1-42) nor ifenprodil changed fEPSPs amplitudes (one-way repeated measures ANOVA with Bonferroni correction) (a). Bar graphs show the mean of the last 5 min of every recording epoch. Error bars represent SEM (b).</div>

Neural Plasticity

fig5

Figure 5

Figure 5: Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors 