Table 1: Summary of factors secreted by microglia and the potential effect they have on neuroprogenitors in vitro.

Microglia secreted
factors
ReferenceModulation of neural progenitor cellsReference

BDNF[18]Differentiation[19]
EGF[20]Survival, expansion, proliferation, differentiation [21]
FGF [22]Survival and expansion[23]
GDNF[24]Survival, migration, and differentiation[25]
IGF-1[21]Proliferation[26]
IL-1 [27]Reduction in migration[27]
IL-6[28]Inhibition of neurogenesis[29]
IL-7[20]Differentiation[30]
IL-11[20]Differentiation[30]
NT-4[24]Differentiation[31]
PDGF[32]Expansion and differentiation[33]
TGF [34]Inhibition of proliferation[19]