Review Article
Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis
Table 2
Summary of factors secreted by neuroprogenitors and the potential effect they have on microglia in vitro.
| NPC secreted factors | Reference | Modulation of microglia | Reference |
| BDNF | [18] | Proliferation and induction of phagocytic activity | [35] | Haptoglobin | [24] | Neuroprotection | [36] | IL-1 | [37] | Intracellular Ca+2 elevation and proliferation | [22] | IL-6 | [37] | Increase in proliferation | [38] | M-CSF | [20] | Mitogen | [39] | NGF | [40] | Decrease in LPS-induced NO | [41] | TGF | [37] | Inhibition of TNF secretion | [42] | TNF | [37] | Upregulation of IL-10 secretion | [43] | VEGF | [20] | Induction of chemotaxis and proliferation | [20] |
|
|