Research Article

Salicylate-Induced Auditory Perceptual Disorders and Plastic Changes in Nonclassical Auditory Centers in Rats

Figure 3

The effects of SS-injection on sound-evoked local field potential (LFP) elicited from electrodes in the Str. (a) An example of LFP at 100 dB SPL recoded before treatment (black filled squares), after saline injection (blue open triangles), and after SS injection (red filled triangles), showing an enhanced response following SS-injection. (b) Mean RMSs of LFP ( ) in a time window of 100 ms as a function of stimulation level, showing progressive increase of LFP amplitude at high stimulation levels but a reduction at low stimulation levels. Acoustic stimulation: 50 ms noise burst; treatments: saline (5 mL/kg, i.p.) and SS (250 mg/kg, i.p.); the vertical bars are standard errors (SEs) and the means ; the arrows indicate increase and decrease of LFP amplitude.
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(a) An example of LFP
658741.fig.003b
(b) Mean LFP response levels