Salicylate-Induced Auditory Perceptual Disorders and Plastic Changes in Nonclassical Auditory Centers in Rats

Figure 4

The effects of SS-injection on the tone-evoked LFP in the Str. (a) Mean RMSs of LFP (𝑛=64) to 12.1 kHz in a time window of 100 ms as a function of stimulation level, showing increase of LFP amplitude at high stimulation levels but a reduction at low stimulation levels. (b) Mean RMSs of LFP (𝑛=64) at 100 dB SPL as a function of stimulation frequency, showing significant enhancement at midfrequencies (3.5–18.3 kHz). Acoustic stimulation: 50 ms tone bursts at different frequencies; treatment: SS (250 mg/kg, i.p.); the vertical bars are SEs and the ∗∗∗ means 𝑃<0.001; the arrows indicate increase and decrease of LFP amplitude.

(a) Mean response levels of LFP to 12.1 kHz

(b) Mean response levels of LFP at 100 dB SPL