Research Article

Salicylate-Induced Auditory Perceptual Disorders and Plastic Changes in Nonclassical Auditory Centers in Rats

Figure 5

The SS effects on unit activity of neurons in the Str. (a) Mean spontaneous discharge rates ( ) as a function of time showing significant decrease after SS injection ( ). (b) An example of peristimulus time histograms (PSTH) obtained before SS (blue) and after SS (red), showing SS-induced increase of discharge rate. (c) Averaged discharge rates of neurons in the Str ( ) in a time window of 100 ms, showing a similar effect of SS injection as the LFP recorded in the nucleus. The discharge rates of each neuron were normalized to that at 0 dB SPL. Acoustic stimulation: 50 ms noise burst; treatment: SS (250 mg/kg, i.p.); the vertical bars are SEs; the arrows indicate increase and decrease of unit activity; ; .
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(a) Spontaneous activity
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(b) An example of response
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(c) Mean discharge rates