Involvement of Thalamus in Initiation of Epileptic Seizures Induced by Pilocarpine in Mice

Figure 5

One example of peri-ictal coupling dynamics between hippocampus and thalamus. (a) Mean values of LFPs recorded from four channels of each tetrode. (b) The directionality index (𝐷_𝑋𝑌) between hippocampus and thalamus. We calculated 𝐷_𝑋𝑌 between each tetrode’s recording from hippocampus and thalamus of the example mouse, getting four combinations. (c) The averaged directionality index (𝐷_𝑋𝑌). The red line indicates the seizure onset time. H, hippocampus; T, thalamus; T1&T2, Tetrode 1 and Tetrode 2 in a bundle.