Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition

Table 1

Summarized patient data for the 3 cohorts of human brain tissue.

Status	ID	Sex	Age	Brain weight (g)	Braak stage
ND	00-137	f	92	1031	1
ND	96-044	f	90	1101	2
ND	98-056	f	83	1000	1
ND	99-052	f	79	1325	2
ND	01-016	m	77	1138	1
ND	01-017	m	79	1334	1
ND	02-087	m	71	1190	1
ND	97-043	m	68	1547	2
Dementia	01-131	f	82	1094	1
Dementia	05-058	f	76	1055	2
Dementia	97-004	f	88	966	2
Dementia	97-047	f	91	1114	1
Dementia	01-075	m	72	1514	1
Dementia	04-022	m	84	1154	2
Dementia	05-004	m	91	1347	1
Dementia	94-090	m	86	1663	2
AD	01-010	f	84	1023	4
AD	03-090	f	87	929	5
AD	05-070	f	77	1178	5
AD	99-095	f	80	1200	6
AD	06-013	m	81	1253	4
AD	06-016	m	72	948	6
AD	93-034	m	78	1315	4
AD	94-121	m	85	1155	4

Hippocampal tissue was obtained from 8 nondemented controls (ND), 8 demented cases with low Braak scores that had suffered from clinical dementia (Dem), and 8 clinically and neuropathologically confirmed senile Alzheimer’s disease cases (AD); Braak staging (ND: Braak 1.4 ± 0.2, Dem: 1.5 ± 0.2, and AD: 4.8 ± 0.3). Cases were matched for age (years) (ND: 80 ± 3, Dem: 84 ± 2, AD: 81 ± 2), postmortem delay, fixation duration, and sex.