Research Article

Neural Plasticity of Mild Tinnitus: An fMRI Investigation Comparing Those Recently Diagnosed with Tinnitus to Those That Had Tinnitus for a Long Period of Time

Table 5

Local maxima for the whole-brain independent sample t-tests in the emotion task experiment. Whole-brain independent sample t-tests were computed for between-group differences. Regions are listed in Montreal Neurological Institute (MNI) coordinates. Brodmann areas are also provided (before determining the Brodmann areas, the MNI coordinates were converted to Talairach coordinates). Statistical threshold was set at FWE corrected for multiple comparisons ( indicates significance at cluster level only). L: left; R: right.

ContrastMNI coordinates
, ,
scoreCluster
mm3
Gyrus (Brodmann area)

LTIN > RTIN (P > N)−16, −12, 325.13117L. middle cingulate gyrus
52, −42, 165.10596R. superior temporal gyrus (BA 22)
54, 18, 305.00348R. middle frontal gyrus (BA 46)
42, −50, 264.85154R. supramarginal gyrus (BA 40)
−40, 2, 404.83246L. middle frontal gyrus (BA 9)
6, 12, 304.82145R. middle cingulate gyrus
−64, −38, 104.81603L. superior temporal gyrus (BA 22)
−22, −12, 524.58248L. middle frontal gyrus (BA 6)

LTIN > RTIN (U > N)No suprathreshold voxels

RTIN > LTIN (P > N)12, −66, 104.58215Posterior cingulate gyrus

RTIN > LTIN (U > N)−32, −20, 124.82365L. insula
38, −12, 364.81265R. precentral gyrus (BA 4)