In Vitro Studies of Neuronal Networks and Synaptic Plasticity in Invertebrates and in Mammals Using Multielectrode Arrays

Figure 2

Example of Helix cultures treated with KCl (a) or 5-HT (b) applications. Each block represents a time-point of recordings (i.e., 6, 72 hours after plating). In the first column, the development of the neurite arborizations is indicated (scale bar is 200 μm). The three columns of raster plots show one minute of electrophysiological activity just before, during, and after the KCl or 5-HT treatment. Red and blue lines indicate recordings from C1 and B2 neurons, respectively. Scale bar is 10 s. Modified from [19].

(a)

(b)