Inhibition of Hyperpolarization-Activated Cation Current in Medium-Sized DRG Neurons Contributed to the Antiallodynic Effect of Methylcobalamin in the Rat of a Chronic Compression of the DRG

Table 1

The effect of MeCbl (10 M) on passive membrane properties of medium-sized DRG neurons.

		Membrane; potential (mV)	Cm (pF)	Rm (MΩ)
Sham	15	−69.00 ± 1.36	64.14 ± 10.93	49.37 ± 8.19
Sham + MeCbl	15	−66.20 ± 1.77	65.83 ± 10.68	48.24 ± 8.17
CCD	17	−66.45 ± 1.22	86.00 ± 19.16	62.74 ± 10.91
CCD + MeCbl	17	−64.12 ± 1.86	77.01 ± 8.84	52.32 ± 8.08

No significant differences in membrane potential, Cm (membrane capacitance), and Rm (membrane resistance) in medium-sized DRG neurons of CCD rats in the presence of MeCbl (, Student’s -test).