Development and Structural Variety of the Chondroitin Sulfate Proteoglycans-Contained Extracellular Matrix in the Mouse Brain

Figure 3

WFA-stained ECM in the developing amygdala. (a–h) WFA-labeled images in the BLA (a–d) and MA (e–h) at P14 (a, e), P21 (b, f), 5 w (c, g), and 11 w (d, h). In both regions, WFA reactivity was observed from P21 onward. (i–n) Higher magnification images of the BLA (i–k) and MA (l–n) at P21 (i, l), 5 w (j, m), and 11 w (k, n). Ambiguous PNN-like staining was observed in the BLA at P21 and 5 w, which surrounded both cell bodies and dendrites at 11 w. Diffuse neuropil-like staining was continuously observed in the MA at all stages shown and a loosely accumulated WFA reactivity around particular cell bodies was observed at 11 w. BLA: basolateral amygdaloid nucleus; MA: medial amygdaloid nucleus. Scale bars = 500 (a–h) and 50 (i–n) μm.

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