Early Maternal Deprivation Enhances Voluntary Alcohol Intake Induced by Exposure to Stressful Events Later in Life

Figure 4

Metabolic parameters during adolescence in response to voluntary alcohol intake. (a) Body weight (BW) gain (g), (b) growth rate (%), and (c) accumulated food intake (g). Rats were exposed to a single episode of early maternal deprivation (24 h on pnd 9, MD) or not deprived (control group, Co) and exposed during adolescence, from postnatal day (pnd) 28 to pnd 50, to voluntary alcohol intake (20% v/v, in a two-bottle choice paradigm). Data are presented as mean ± S.E.M and were analyzed by a repeated measures two-way ANOVA (BW gain and growth rate) or by a two-way ANOVA (accumulated food intake). ; (A) general effect of sex and (B) general effect of the neonatal condition; –20 animals per experimental group.

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