The Morphofunctional Effect of the Transplantation of Bone Marrow Stromal Cells and Predegenerated Peripheral Nerve in Chronic Paraplegic Rat Model via Spinal Cord Transection

Figure 3

Photomicrography of the expression of GAP-43 in spinal cord. (a) Control group. (b) Fibrin glue group (FG). (c) PPN group, rostral zone of the SC. (d) PPN + BMSCs group, rostral zone of the SC. (e) PPN group, caudal zone of the SC. (f) PPN + BMSCs group, caudal zone of the SC. A greater quantity of GAP-43 positive fibers can be observed in panels (c) to (f) (white arrows, Alexa 488, green color), compared to panels (a) and (b). Furthermore, and easily visible, the positive fibers which were found in the PPN + BMSCs group ((e) and (f)) are thicker than those ones which were in the PPN group ((c) and (d)). All the tissue was contrasted with propidium iodide (nuclei red color). Calibration bar 20 μm.

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