α7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin Neurotoxicity

Table 1

Astrocyte monoculture. Pyruvate intracellular levels.

Pyruvate (%)
Control	Oxaliplatin (1 M)	PNU; (10 M)	Oxaliplatin (1 M) +; PNU (10 M)
100.0 ± 16.3	545.9 ± 56.	129.8 ± 25.3	496.5 ± 38.

Pyruvate intracellular concentration was measured in astrocyte monoculture. Cells were treated with 1 M oxaliplatin (48 h) in the absence or presence of 10 M PNU. Values are expressed in percentage of control as mean ± S.E.M. of 6 experiments. Control condition was fixed to 100%. One-way ANOVA was performed followed by a Bonferroni significant difference procedure. versus control.