Altered Intra- and Interregional Synchronization in Resting-State Cerebral Networks Associated with Chronic Tinnitus

Figure 2

Relationships between abnormal functional connectivity and tinnitus distress. ((a)-(b)) The functional connectivity of left AI to left MFG was correlated with the THQ score (, ). (c) The aberrant brain connectivity networks from four seed regions. The red represents the left AI; the magenta represents the right AI; the yellow represents the left IFG; the green represents the right SMG. ((d)-(e)) The functional connectivity of right AI to right MFG was correlated with the THQ score (, ). L: left; R: right; THQ: Tinnitus Handicap Questionnaires; AI: anterior insula; IFG: inferior frontal gyrus; SMG: supramarginal gyrus; MFG: middle frontal gyrus; STG: superior temporal gyrus; ITG: inferior temporal gyrus; ACC: anterior cingulate cortex; PCC: posterior cingulate cortex; OFC: orbitofrontal cortex.