Neuroplasticity Underlying the Comorbidity of Pain and Depression

<div>Brain regions and circuits implicated in the comorbidity between pain and depression. ACC: anterior cingulate cortex; AMY: amygdala; IC: insular cortex; NAc: nucleus accumbens; PAG: periaqueductal gray; PFC: prefrontal cortex; RVM: rostral ventromedial medulla; S1: primary somatosensory cortex; S2: secondary somatosensory cortex.</div>

Neural Plasticity

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Figure 1

Figure 1: Neuroplasticity Underlying the Comorbidity of Pain and Depression 