Synaptic Variability Introduces State-Dependent Modulation of Excitatory Spinal Cord Synapses

Figure 2

(ai) Graph showing the amplitude of the initial EPSP at connections that were potentiated or reduced by substance P. On this and other graphs, the asterisk indicates a statistically significant difference. Sample traces show connections where substance P potentiated (aii) or reduced (aiii) the initial EPSP amplitude. (b) Graph showing the significant negative relationship between the initial EPSP amplitude and the magnitude of the EPSP potentiation. (c) Graph showing the lack of a significant relationship between the initial EPSP amplitude and the magnitude of the EPSP reduction.