Statins Promote Long-Term Recovery after Ischemic Stroke by Reconnecting Noradrenergic Neuronal Circuitry

<div>Immunoreactivity of WGA in the tFCI mouse brain. WGA immunoreactivity at 30, 180, and 240 days after tFCI in the vehicle- and atorvastatin-treated groups showed that NA circuitry in the atorvastatin-treated group recovered faster than in the vehicle-treated group at 180 days. aci: anterior commissure, intrabulbar part; hf DG: hippocampal fissure and dentate gyrus; LHb: lateral habenular nucleus; Op: optic nerve layer of the superior colliculus; InWh: intermediate gray layer of the superior colliculus. Scale bar = 500 <i>μ</i>m.</div>

Neural Plasticity

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Figure 2

Figure 2: Statins Promote Long-Term Recovery after Ischemic Stroke by Reconnecting Noradrenergic Neuronal Circuitry 