Localization of Presynaptic Plasticity Mechanisms Enables Functional Independence of Synaptic and Ectopic Transmission in the Cerebellum

Figure 7

Effect of activation of mGluR1 on Bergmann glial responses. (a) Representative whole-cell recordings ESCs generated by paired pulse stimulation (100 ms interval) of parallel fibres in transverse cerebellar slices at 0.033 Hz before (first panel), after 5 minutes incubation with 30 μM DHPG (second panel), and after 10 minutes of washout (third panel). (b) Time course of 30 μM DHPG effect on amplitude of the first pulse in each pair, with DHPG incubation at the time indicated by the bar. Data are mean ± s.e.m. from 7 cells. , one-sample -test. (c) Time course of 30 μM DHPG effect on paired pulse ratio, with DHPG incubation at the time indicated by the bar. Data are mean ± s.e.m. from 7 cells.

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