Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury

Figure 7

Human NSPCs express diverse trophic factors. (a) In vitro, proliferating (Prol) and differentiated (Diff) hNSPCs, respectively, expressed FGF2, GDNF, VEGF, and neurotrophins including BDNF, NT3, NTF4, and NGF. (b) hNSPCs notably secreted BDNF, NT3, NT4/5, NGF, and VEGF into the cultured media, compared to human foreskin fibroblasts (Fib).

(a)

(b)