Clinical Trial of Human Fetal Brain-Derived Neural Stem/Progenitor Cell Transplantation in Patients with Traumatic Cervical Spinal Cord Injury
Table 10
Latency measured by evoked potentials of the upper and lower limbs in patients with cervical SCI who showed response of SSEP over 1 year after hNSPC transplantation.
Patient
Before
2 months
6 months
1 year
Right
Left
Right
Left
Right
Left
Right
Left
Median nerve
1
0.00
0.00
0.00
0.00
0.00
0.00
19.00
17.95
2
0.00
0.00
0.00
0.00
33.15
22.95
25.15
31.50
10
0.00
0.00
17.80
18.75
19.40
16.00
17.71
20.95
15
0.00
0.00
19.00
18.65
0.00
0.00
0.00
0.00
Ulnar nerve
1
0.00
0.00
0.00
0.00
0.00
0.00
23.40
28.95
2
0.00
0.00
0.00
0.00
26.40
0.00
24.85
0.00
4
0.00
0.00
0.00
0.00
37.30
35.30
22.20
23.95
6
0.00
0.00
16.10
0.00
18.05
0.00
18.50
0.00
7
0.00
0.00
0.00
0.00
0.00
0.00
19.35
20.65
10
0.00
0.00
20.10
25.50
18.85
19.35
17.05
20.25
5
0.00
0.00
0.00
0.00
20.90
21.60
0.00
0.00
8
0.00
0.00
27.95
27.95
0.00
0.00
0.00
0.00
15
0.00
0.00
19.45
18.15
0.00
0.00
0.00
0.00
Tibial nerve
7
0.00
0.00
0.00
0.00
0.00
0.00
61.90
43.10
15
0.00
0.00
42.70
44.70
0.00
0.00
0.00
0.00
Peroneal nerve
7
0.00
0.00
0.00
0.00
0.00
0.00
44.80
44.60
15
0.00
0.00
39.10
48.00
0.00
0.00
0.00
0.00
Pudendal nerve
7
0.00
0.00
0.00
61.80
19
0.00
0.00
44.40
48.00
Right side, left side, ms, and patients showed recovery of SSEPs at 2- or 6-month follow-up times. However, the cortical response to peripheral stimulation disappeared at 1 year after transplantation. There is no division into right and left side in pudendal nerve stimulation.