CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex

<div>Whisker trimming procedure. Cartoon depicting the whisker trimming protocol. Wild type and mCREB mice underwent 14 days of unilateral whisker deprivation starting at 30 days of age or left undisturbed in their home cage (<i>Naïve</i>). PND: postnatal day. At the end of trimming period, brains were separated and the two hemispheres were identified as ipsilateral (<i>Ipsi</i>) or contralateral (<i>Contra</i>) to trimmed mystacial pad.</div>

Neural Plasticity

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Figure 1

Figure 1: CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex 