Multiscale Modeling Indicates That Temperature Dependent [Ca²⁺]_i Spiking in Astrocytes Is Quantitatively Consistent with Modulated SERCA Activity

Figure 6

Cell characteristics in the rate equation model. Dependence of the period (a), amplitude (b), and spike width (c) on the SERCA pump strength for three different Ca²⁺ release rates from IP₃ channels.

(a)

(b)

(c)