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Neural Plasticity
Volume 2015, Article ID 684025, 10 pages
http://dx.doi.org/10.1155/2015/684025
Clinical Study

The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase

1Center for Clinical and Epidemiological Research & Interdisciplinary Center for Applied Neuromodulation (CINA), University Hospital, University of São Paulo, São Paulo, Brazil
2Service of Interdisciplinary Neuromodulation (SIN), Department and Institute of Psychiatry, Faculty of Medicine of University of São Paulo, São Paulo, Brazil
3Laboratory of Neuroscience (LIM27), Department and Institute of Psychiatry, University of São Paulo, São Paulo, Brazil
4Bipolar Disorder Research Program, Department and Institute of Psychiatry, University of São Paulo Medical School, Brazil
5Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health (NIMH), NIH, Bethesda, MD, USA
6Hospital Universitário, Cidade Universitária, Universidade de São Paulo, Avenida Professor Lineu Prestes 2565, No. 3 Andar, 05508-000 São Paulo, SP, Brazil

Received 24 October 2014; Accepted 11 January 2015

Academic Editor: Benício N. Frey

Copyright © 2015 Bernardo de Sampaio Pereira Junior et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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