Sensory Deprivation during Early Postnatal Period Alters the Density of Interneurons in the Mouse Prefrontal Cortex

<div>Effects of sensory deprivation on PV neurons in the PL at P56. Whisker trimmed mice (b), dark reared mice (c), and whisker trimmed and dark reared mice (d) have more PV neurons than intact mice (a). (A)–(D) Higher magnification images of PV neurons in the PL. Intact: intact control, trim: whisker trimming, dark: dark rearing, and trim + dark: whisker trimming plus dark rearing. Scale bars = 200 <i>μ</i>m in (d) (applies to (a)–(d)); 50 <i>μ</i>m in (D) (applies to (A)–(D)).</div>

Neural Plasticity

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Figure 5

Figure 5: Sensory Deprivation during Early Postnatal Period Alters the Density of Interneurons in the Mouse Prefrontal Cortex 