Plasticity of Neuron-Glial Transmission: Equipping Glia for Long-Term Integration of Network Activity

Figure 1

Modes of neuron-glial transmission and plasticity. Summary of the routes for neuron-glial transmission in which long-term plasticity after electrical stimulation of presynaptic cells has been demonstrated. Left panel shows synaptic transmission for NG2 cells (analogous to classical neuronal LTP), middle panel shows ectopic transmission at cerebellar Bergmann glia, and right panel shows volume transmission through diffusion to extrasynaptic receptors. The table shows cell types, receptors, stimulation protocols, and forms of glial plasticity that have been described. See main text for references and further details.