Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

Table 4

Diffusivity parameters in the corpus callosum: before and after intervention and at six weeks following bimanual intervention.

Case	Genu						Midbody						Splenium
	MD (×10^−3 mm^2/s)			FA (a.u.)			MD (×10^−3 mm^2/s)			FA (a.u.)			MD (×10^−3 mm^2/s)			FA (a.u.)
Camp intervention	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up
1	0.85	0.86	0.85	0.63	0.61	0.62	0.85	0.82	0.83	0.59	0.61	0.59	0.8	0.79	0.82	0.67	0.68	0.66
2	1.02	1.05	—	0.56	0.57	—	1.07	1.06	—	0.48	0.48	—	1.12	1.16	—	0.49		—
3	1.01	1.02		0.57	0.57	0.57	1.24			0.48		0.44	0.96		0.99	0.63	0.63	0.59
4	0.89	0.88	0.89	0.6	0.6	0.59	0.93			0.58	0.58	0.56	1.04	1.02	1.19	0.54
5	0.84	0.86	0.86	0.61	0.61	0.6	0.78	0.79	0.82	0.62	0.61	0.59	0.8	0.8	0.83	0.66	0.65	0.64
6	0.92		0.9	0.54			0.94	0.93	0.98	0.49	0.5	0.52	1.11			0.47	0.43	0.45
7	0.97	1.01	1	0.6	0.63	0.57							0.95			0.67	0.69	0.68
8	0.91	0.92	—	0.59	0.6	—	0.93	0.92	—	0.6	0.6	—	0.84	0.91	—	0.7	0.69	—
Home intervention	Before	After		Before	After		Before	After		Before	After		Before	After		Before	After
9	0.92	0.99		0.61			0.89	0.85		0.57	0.58		1.04			0.56
10	0.95	0.92		0.59	0.6		0.84	0.86		0.62	0.59		0.75	0.75		0.7	0.7
11	0.9	0.96		0.59	0.59		1.1			0.55	0.57		0.82	0.81		0.67	0.69
12	—	—		—	—

MD = mean diffusivity (×10⁻³ mm²/s); FA = fractional diffusivity (arbitrary units).
Significant improvement >5% from baseline.
Due to large lesion size, we were unable to reconstruct this segment.