Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence

Table 5

Diffusivity parameters in the affected corticospinal tract at 3 time points.

	Affected CST						Less affected CST
Case	MD (×10^−3 mm^2/s)			FA (a.u.)			MD (×10^−3 mm^2/s)			FA (a.u.)			Behavior improv.
	T1	T2	T3	T1	T2	T3	T1	T2	T3	T1	T2	T3
Camp intervention	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up	Before	After	Follow-up
1	0.79		0.76	0.59	0.6	0.59	0.77	0.74	0.76	0.61	0.62	0.61	Yes
2							0.8		—	0.56		—	Yes
3	0.8	0.84	0.81	0.55	0.55	0.55	0.8		0.8	0.54		0.56	Yes
4	0.79	0.85	0.84	0.58	0.6		0.88			0.62	0.58		Yes
5	0.73	0.74	0.78	0.61	0.58	0.6	0.72	0.71	0.75	0.6	0.6	0.6	Yes
6							0.76	0.74	0.74	0.59	0.58	0.6	No
7	0.84		0.82	0.6		0.62	0.74	0.73	0.75	0.62	0.6	0.65	Yes
8	0.89	0.87		0.56	0.56		0.73	0.76		0.62	0.62		Yes
Home intervention	Before	After		Before	After		Before	After		Before	After
9	0.83			0.6			0.76			0.61			Yes
10	0.79	0.82		0.62	0.58		0.79			0.65	0.61		Yes
11	0.81	0.81		0.62	0.6		0.75	0.76		0.63	0.6		Yes
12	—	—		—	—		—	—		—	—		Yes

MD = mean diffusivity (×10⁻³ mm²/s); FA = fractional diffusivity (arbitrary units). Significant improvement = >5% improvement. Due to large lesion size, we were unable to reconstruct this tract.