Cytomegalovirus Antibody Elevation in Bipolar Disorder: Relation to Elevated Mood States

Table 3

Here we provide CMV IgG concentrations (reported as mean ± standard deviation in column 2) for each diagnosis, BD-I and healthy controls.

Diagnosis	CMV IgG concentrations	Diagnostic comparison of CMV	CMV IgG seropositivity		Pearson chi-square
	Mean ± SD	Antibody concentrations	Seronegative	Seropositive	Testing
Healthy control volunteers	()				Likelihood ratio = 5.2
Bipolar disorder type I	()

Results of independent samples T-testing are reported in column 3. We identify significantly greater concentration of CMV IgG in BD-I volunteers as compared to healthy control volunteers (, , and ). Chi-squared testing confirmed that CMV IgG seropositivity status was associated with 5.2 times greater likelihood of the presence of a diagnosis of BD-I (). Neither HSV-1 nor HSV-2 differed significantly between the BD-I and healthy control groups.