CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation

Figure 7

Diagram of a model for CRMP2 and CRMP4 coordinately regulating growth cone development and axon elongation via cytoskeleton dynamics. The schematic model shows that CRMP2 and CRMP4 may form complexes (homo- or heterotetramers) bridging microtubules and actin to mediate cytoskeleton dynamics, thus regulating growth cone development and axon elongation.