TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch

Figure 6

AMG9810 and U73122 inhibited immepip-induced scratching in mice. The histogram shows bouts of scratching by injection of immepip 100 μmol and saline 100 μL/site () (a). (b) Saline (PBS) 100 μL/site or AMG9810 5 μM 100 μL/site 30 minutes pretreated before immepip subcutaneous injection. Saline (PBS) 100 μL/site or U73122 1 μM 100 μL/site 30 minutes pretreated before immepip subcutaneous injection in (c). The data are presented as mean ± SEM ().

(a)

(b)

(c)