Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals

Table 1

Clinical data of control and Alzheimer’s disease individuals investigated in the methylation study.

	Age at death (years)	Gender	CDR	Stages of senile changes			Cause of death
				Braak	CERAD	LB
Controls
1	81	F	0	0	0	—	Pulmonary edema
2	97	F	0	0	0	—	Pulmonary embolism
3	85	M	0	0	0	—	Acute myocardial infarction
4	83	M	0	0	0	—	Pulmonary edema
5	83	M	0	0	0	—	Pulmonary edema
6	81	F	0	0	0	—	Acute myocardial infarction
7	85	M	0	0	0	—	Pulmonary edema
8	83	M	0	0	0	—	Ischemic myocardial disease
9	77	F	0	0	0	—	Acute myocardial infarction
10	81	F	0	0	0	—	Acute myocardial infarction
Alzheimer’s disease
1	84	F	3	6	C	—	Pulmonary edema
2	82	M	3	6	C	—	Ischemic myocardial disease
3	80	M	3	5	C	—	Pulmonary edema
4	83	F	3	6	C	—	Pulmonary embolism
5	79	F	3	6	C	—	Pneumonia
6	86	F	3	5	C	—	Pneumonia
7	94	F	3	6	C	—	Pulmonary edema
8	83	F	3	6	C	—	Pulmonary embolism
9	80	F	3	5	C	—	Pulmonary edema
10	83	F	3	6	C	—	Pneumonia

Braak stage = neurofibrillary tangle; CERAD (Consortium to Establish a Registry for Alzheimer’s Disease) = neuritic plaques; LB = Lewy body; CDR = Clinical Dementia Rate.