Research Article

Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice

Figure 2

Detection of glutamatergic and GABAergic terminals in DCN. The large DCN neurons are enwrapped by aggrecan-based ECM (red). (a) DCN neurons are innervated by GABAergic boutons, labeled by GAD 65/67. GABAergic terminals seem to be reduced in pcd. (b) The glutamatergic boutons at DCN neurons are discovered by moderate vGlut 1 and vGlut 2 staining. The staining in pcd appears slightly enhanced. Scale bar: 20 μm.
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