NLRP3 Is Expressed in the Spiral Ganglion Neurons and Associated with Both Syndromic and Nonsyndromic Sensorineural Deafness

Figure 3

The p.E313K (c.G937A) mutation of NLRP3. (a) Chromatograms of the mutant and wild-type sequences. (b) Conservation of the E313 residue of NLRP3 in Homo sapiens, Pan troglodytes, Felis catus, and Mus musculus. (c) Domain structure of NLRP3 protein with the location of the p.E313K mutation marked by an arrow.

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