A Comparative Analysis of the Endocannabinoid System in the Retina of Mice, Tree Shrews, and Monkeys

Figure 3

CB1R immunoreactivity in rod bipolar cells. Vertical sections taken from the mouse retina (first column), tree shrew retina (second column), vervet retina (third column), and macaque retina (fourth column). Confocal micrographs of coimmunolabeling for CB1R and the cell-type-specific marker for rod bipolar cells, protein kinase C alpha (PKCα). Each protein expression is presented alone in grayscale: CB1R in the first line and PKCα in the second line; then the two are presented merged (third line: CB1R in magenta and PKCα in green). Arrows point to dendrites ascending into the OPL, where rod spherules are found, and arrowheads point to synaptic terminals in the IPL. INL: inner nuclear layer; IPL: inner plexiform layer. Scale bar = 30 μm.