Polarity Determinants in Dendritic Spine Development and Plasticity

Figure 4

Asymmetric localization of core planar cell polarity (PCP) proteins in the fly wing. (a) Cells can polarize within the plane of the epithelial sheet, a phenomenon called planar cell polarity. (b) The core PCP proteins Frizzled and Vang form transcellular interactions and are distributed asymmetrically along the epithelial plane. Vang is concentrated in the proximal membrane while Frizzled is localized to the distal membrane.

(a)

(b)