Dysfunction in Ribosomal Gene Expression in the Hypothalamus and Hippocampus following Chronic Social Defeat Stress in Male Mice as Revealed by RNA-Seq

Figure 3

Differentially expressed mitochondrial ribosomal Mrps and Mrpl genes in the hypothalamus of mice following CSDS. The Cufflinks program was used to estimate the gene expression levels in FPKM. The levels of the Mrps and Mrpl gene expression are presented in the control (left columns) and depressive mice (right columns). The Mrpl54, Mrpl12, Mrpl38, Mrpl52, Mrpl28, Mrpl23, Mrpl34, Mrpl4, Mrps18a, Mrps12, Mrps18a, and Mrps12 genes were upregulated, whereas Mrpl1 and Mrpl3 were downregulated. Statistical significance and . ; .