Figure 5: The effect of LTP induction on paired-pulse responses; data are collapsed across rearing conditions. LTP induction resulted in significant enhancement of PPD at ISIs of 25 to 250 ms. ANOVA results: effect of ISI, F(2.34, 39.85) = 4.16, ; effect of LTP induction, F(1.00, 17.00) = 11.11, ; effect of ISI by LTP interaction, F(3.38, 57.48) = 4.14, . Inserts (a) and (b) show the effect of LTP for control and WN-reared rats, respectively; indicates significant simple effects, .