Dynamic Changes in Local Protein Synthetic Machinery in Regenerating Central Nervous System Axons after Spinal Cord Injury

Figure 4

Translational machinery in reinjured and actively growing axons is comparable. Graphs (a)–(e) show quantification of relative immunolabeling intensity for the subtracted axon-only signals for 4EBP1, p4EBP1, eIF2α, peIF2α, and pS6, respectively. Data are expressed as fold change in signal intensity after reinjury at 7-week compared with 3-week PNGs ± SD, using Holm-Šídák post hoc test. No significant differences were seen between the two groups; however the levels of pS6 between the two groups trended towards significance ().

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