Research Article
Early Transcriptional Changes Induced by Wnt/β-Catenin Signaling in Hippocampal Neurons
Table 1
Top 20 nominal significant Wnt3a-upregulated genes in hippocampal neurons.
| | Symbol ID | FC | value | Wnt pathway | References |
| | Fam84a | 2.4 | 2.2 × 10−6 | — | — | | Notum | 14.1 | 1.5 × 10−5 | Wnt target gene | [45] | | Lef1 | 2.1 | 1.7 × 10−5 | Wnt target gene | [46] | | Axin2 | 3.5 | 1.2 × 10−4 | Wnt target gene | [47] | | Prkg2 | 2.7 | 1.4 × 10−4 | Functional | [48] | | Cxcl3 | 4.6 | 5.2 × 10−4 | Wnt target gene | [49] | | Ahr | 2.1 | 1.0 × 10−3 | Wnt target gene | [50] | | Stk32a | 1.8 | 1.3 × 10−3 | — | — | | Itga9 | 2.0 | 1.7 × 10−3 | — | — | | Tnfresf19 | 2.4 | 1.8 × 10−3 | Wnt target gene | [51] | | Tmem72 | 1.7 | 2.0 × 10−3 | — | — | | Fras1 | 1.9 | 2.2 × 10−3 | — | — | | Fam167a | 1.8 | 2.2 × 10−3 | — | — | | Gata2 | 2.8 | 2.3 × 10−3 | Wnt target gene | [52] | | Id2 | 1.3 | 3.0 × 10−3 | Wnt target gene | [53] | | Msx2 | 2.1 | 3.9 × 10−3 | Wnt target gene | [54] | | Sp5 | 10.3 | 4.2 × 10−3 | Wnt target gene | [55] | | Cd83 | 2.1 | 4.4 × 10−3 | — | — | | Cgnl1 | 1.5 | 4.9 × 10−3 | — | — | | Hunk | 1.5 | 5.3 × 10−3 | Wnt target gene | [56] |
|
|
Functional: known to modulate Wnt pathway transcriptional activity. FC: fold change.
|
