Research Article
Early Social Enrichment Improves Social Motivation and Skills in a Monogenic Mouse Model of Autism, the Oprm1−/− Mouse
Table 1
Mean (±SEM) body weight (gr.) of mice (males and females) belonging to the four experimental groups.
| Experimental groups | Oprm1 | Oprm1 | ANOVA | L | L+L | L | L+L | G | RC | S |
| Day 8 | | | | | | | | Males | 4.68 ± 0.15 | 5.99 ± 0.23 | 4.60 ± 0.24 | 6.49 ± 0.10 | 0.78 | 152.02 | 0.14 | Females | 4.68 ± 0.20 | 6.31 ± 0.17 | 4.65 ± 0.17 | 6.40 ± 0.16 |
| | | | | | ANOVA | | | | | | G | E | S |
| Days 28–30 | | | | | | | | Males | 16.32 ± 0.48 | 14.08 ± 0.51 | 14.86 ± 0.79 | 15.03 ± 0.89 | 1.69 | 1.41 | 0.21 | Females | 15.64 ± 0.44 | 15.06 ± 0.56 | 14.17 ± 0.29 | 14.54 ± 0.66 |
| | | | | | ANOVA | | | | | | G | E | S |
| Days 75–80 | | | | | | | | Males | 27.17 ± 0.59 | 28.06 ± 0.41 | 25.75 ± 0.87 | 26.68 ± 0.54 | 0.68 | 0.53 | 90.42 | Females | 21.36 ± 0.31 | 21.75 ± 0.30 | 22.39 ± 0.82 | 21.74 ± 0.53 |
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G: genotype; RC: rearing condition; S: sex. , . Sample sizes are reported in brackets.
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