Coordinated Plasticity between Barrel Cortical Glutamatergic and GABAergic Neurons during Associative Memory

Figure 9

Mutual innervation between excitatory and inhibitory neurons is upregulated after associative learning. (a) shows YFP-labeled axon terminals on a GFP-labeled GABAergic neuron (left panel) and its process (middle) as well as GFP-labeled axon terminals on YFP-labeled apical dendrite of a glutamatergic neuron (right) from controls. (b) shows YFP-labeled axon terminals on a GFP-labeled GABAergic neuron (left panel) and its process (middle) as well as GFP-labeled axon terminals on YFP-labeled dendrite of a glutamatergic neuron (right) from CR-formation. White arrows indicate their termination. (c) shows YFP-labeled axon terminals on each GABAergic neuron in control (white bar) and CR-formation (gray, two asterisks, , ). (d) shows YFP-labeled axon terminals per 100 μm GFP-labeled dendrite of GABAergic neurons in controls (white bar) and CR-formations (gray, three asterisks, , ). (e) shows GFP-labeled axon terminals per 100 μm YFP-labeled apical dendrite of glutamatergic neurons in controls (white bar) and CR-formations (gray, two asterisks, , ).

(a)

(b)

(c)

(d)

(e)