Regeneration of Zebrafish CNS: Adult Neurogenesis

Figure 4

Analysis of cyclins and Cdks during spinal cord regeneration. (a) Schematic diagram shows cell cycle regulatory genes expressed during adult zebrafish spinal cord regeneration [23]. (b) Expression pattern of various cell cycle regulatory genes based on microarray analysis during spinal cord regeneration [23]. Several cyclins associated with different cell cycle phases are shown such as cyclin D1 (G1), cyclin E (S), cyclin A2 (G2), cyclin H (G2), Cdk7 (G2), cyclin B1 (G2-M), cyclin B2 (G2-M), and Cdkl1 (G2-M). (c) Heat maps of cell cycle regulatory genes expressed during regeneration showing different temporal pattern.